Native Proteins and Derivatives
BioVendor, LLC Uromodulin (Tamm-Horsfall urinary glycoprotein, THP), Canine Native protein, 0.1 mg
Uromodulin (Tamm-Horsfall urinary glycoprotein, THP), Canine Native protein, 0.1 mg
Biotium Primary Antibody CD227 EMA Episialin Mucin 1 GP1.4 CF740 1/EA
In Western blotting this antibody recognizes proteins in MW range of 265-400 kDa identified as different glycoforms of EMA This MAb reacts with the DTRP epitope in the tandem repeats Thealpha subunit has cell adhesive properties It can act both as an adhesion and an anti-adhesion protein EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack The beta subunit contains a C-terminal domain which is involved in cell signaling through phosphorylations and protein-protein interactions In immunohistochemical assays it superbly stains routine formalin/paraffin carcinoma tissues Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low
Biotium Primary Antibody Fibronectin TV-1 CF740 1/EA
Fibronectin is a soluble dimeric glycoprotein of 440 kDa which is present in cells extracellular matrix and blood This MAb reacts with the cellular as well as plasma form of fibronectin Reportedly after iv administration this MAb localizes to tumor vessels where it binds to the underlying basement The epitope recognized by this antibody is not accessible to the circulating MAb in normal tissues indicating that it can be used to specifically target tumor vessels in vivo TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets because blue dyes have lower fluorescence and can give higher
Biotium Primary Antibody Fibronectin HFN7.1 CF740 1/EA
Fibronectin is a dimeric glycoprotein of 440 kDa which is present in cells extracellular matrix and blood It possesses at least four binding sites for collagen glycosaminoglycans transglutaminase and a cell surface receptor Fibronectin is involved in cell adhesion tissue organization and wound healing This MAb is directed against the peptide core and reacts with both the plasma and cellular forms of fibronectin It blocks the fibronectin-medicated cell attachment not by disrupting the collagen-fibronectin interaction but by interfering with the attachment of fibronectin to its receptor on the cell surface Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors
Medchemexpress LLC PLAU/uPA Rat HEK29 5ug
PLAU/uPA proteins lack conserved residues critical for feature annotation propagation suggesting potential differences in molecular interactions in plasminogen activation and fibrinolysis regulation PLAU/uPA Protein Rat (HEK293 His) is the recombinant rat-derived PLAU/uPA protein expressed by HEK293 with C-His labeled tag
Cayman Chemical CathepsIn BhumnrecombIna 50ug
Source: Active recombinant human C-Terminal His-tagged cathepsin B expressed in HEK293 cells • Amino acids: 74-339 • MW: 37.2 kDa
Vector Biolabs Mitogen-activated protein kinase 3 Adenovirus (Ad-ERK1)
The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42, which are encoded by ERK 1 and ERK 2, respectively. Both proteins are regulated by dual phosphorylation on specific tyrosine and threonine residues mapping within a characteristic Thr-Glu-Tyr motif. In response to activation, both MAP kinases phosphorylate downstream components on serine and threonine. Upstream MAP kinase regulators include MAP kinase kinase (MEK), MEK kinase and Raf-1. ERK 3 is a MAP kinase-related protein. The human homolog of ERK 3 has also been cloned and shown to encode a 97 kDa protein. ERK 5 has been identified as an 815 amino acid protein that functions as a substrate for MEK-5, but not for MEK-1 or MEK-2. ERK 6 (also designated SAPK3) is highly expressed in human skeletal muscle and appears to function as a signal transducer during differentiation of myoblasts to myotubes.
Cayman Chemical CalpaIn InhIbItr III 50mg
A cell permeable, selective inhibitor of μ-calpain (calpain-1) and m-calpain (calpain-2); crosses the blood-brain barrier to inhibit brain cysteine protease activity; reported to have protective effects in numerous rodent models of neurotrauma and cardiac ischemia
Innovative Research Inc Hmn Plasmin Immobilized 1ml
Human Plasmin Immobilized 1ml - Human Plasmin Immobilized has been purified from Human Plasma using affinity chromatography then immobilized to an agarose support. This is a resin buffered in 0.1M HEPES; 0.1M NaCl; 0.02% Sodium Azide; pH 7.4 coupled and a purity of >95%. This product is useful activation of single-chain tPA and uPA to the two-chain form and conversion of plasminogen from its native Glu form to the Lys form by removing the first 77 amino acids. More Details Source Human Plasma Purification Chromatographically purified Purity >95% Storage Conditions 4 C
Medchemexpress LLC MUC-17 Human HEK29 50ug | 50ug
MUC-17 protein maintains mucosal homeostasis contributing to environmental stability Interacting via its C-terminus MUC-17 crucially associates with PDZK1 ensuring proper cellular localization MUC-17 Protein Human (HEK293 His) is the recombinant human-derived MUC-17 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Clusterin (apolipoprotein J), human recombinant protein (HEK293, Fc-His) | >90.0% | 100 UG
Recombinant human clusterin (apolipoprotein J) expressed in HEK293 cells and supplied lyophilized with Fc and His tags. The product corresponds to UniProt P10909-1 (D23-E449) and is intended for laboratory research use only; not for clinical or human use.
- Expressed in HEK293 cells.
- Contains Fc fragment and C-terminal His tag.
- Amino acid range D23-E449 (UniProt P10909-1).
- Purity greater than 90% by reducing SDS-PAGE.
- Lyophilized formulation from PBS/20 mM PB with trehalose and mannitol.
- Store at -20°C; stable 2 years from receipt; aliquot and freeze for long term.
- Do not reconstitute below 100 μg/mL in ddH2O; add carrier protein for long-term storage.
Biolegend Recombinant Human Activin A ca
Recombinant Human Activin A (carrier-free); Reactivity: Human; Apps: BA; Size: 25 μg
Antibodies Online TXNDC12 Protein (AA 27-168) (His tag) 50ug
Recombinant Human Thioredoxin Domain-Containing Protein 12/TXNDC12 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (His27-Leu168) of Human TXNDC12 fused with a polyhistidine tag at the C-terminus.
Cayman Chemical 2OMethylgunosIn5OtrI 2.7mg
An HCV NS5B inhibitor (IC50 = 3.5 µM) and active metabolite of IDX184; induces tubulin polymerization at 50 µM; tumoral levels are decreased in patients with hepatocellular carcinoma compared with adjacent normal tissue
